Indomethacin

About Indomethacin

Indomethacin is a non-steroidal anti-inflammatory drug (NSAID).

Indomethacin is used to manage fever, pain, and swelling. It is also used to manage diseases of the bones and joints, such as rheumatoid arthritis, gout, and osteoarthritis.

How does Indomethacin work?

Pain and swelling are due to the activity of chemicals known as prostaglandins at the site of injury. Prostaglandins increase pain sensitivity.

Proteins known as COX help in the production of prostaglandins. Indomethacin blocks the action of COX.

What are the side-effects I may experience?

You may experience:

• Diarrhea

• Nausea

• Stomach ache

• Vomiting

• Headache

Are there any medications and foods I should avoid?

You can eat normally when taking indomethacin. It is advisable to take indomethacin after meals or with meals.

You should avoid excessive alcohol intake. Stomach irritation may be experienced when alcohol is consumed with indomethacin.

Without permission from your doctor or pharmacist, you should avoid taking indomethacin if you are an asthmatic, have ulcers, or have experienced a stroke or heart attack.

Indomethacin can worsen stomach ulcers. The safest painkiller with the least side-effects is paracetamol. It can also increase your chances of having a heart attack or having a stroke.

I forgot a dose. What should I do?

If you forget to take your prescription, take it as soon as you remember.

If you miss a dose, don’t take a double dose.

If your next dose is approaching, skip the missed dose and take the next one.

Can I drive or operate machinery?

Indomethacin can cause drowsiness and alter your vision. You shouldn’t drive or operate machinery if you experience this side-effect.

Should I be bothered about possible addiction or dependence?

Indomethacin isn’t addictive.

Will my sexual performance, fertility or contraceptive be impaired?

• Indomethacin may affect ovulation and impair female fertility when used continuously for a long time. This effect goes away when you stop taking indomethacin.
• It isn’t recommended for more than a week in women attempting to get pregnant or for women who have difficulties getting pregnant.
• Ibuprofen doesn’t affect your sexual performance or contraceptives.

Can I use this medication if I am pregnant or breastfeeding?

• Indomethacin can cause harm to your unborn baby. You should avoid indomethacin during pregnancy unless prescribed by your doctor.

  Indomethacin can prolong your bleeding and affect your contractions. This can delay or prolong labor.

  Paracetamol is the safest pain killer to use when pregnant.

• Very small amounts of indomethacin are in breast milk. Indomethacin is unlikely to harm your baby.

  You should inform your pharmacist or doctor before taking indomethacin when breastfeeding.